Royal Air Force Typhoon FGR4s have conducted a mission with French aircraft in a coordinated attack targeting an subterranean weapons facility in Syria used by the IS group, as stated by the UK Ministry of Defence.
The site, located using surveillance, was believed to be housing weapons and explosive materials, the announcement noted, and was located in hills just to the north of the ancient city of Palmyra in central Syria.
"Our aircraft employed precision-guided Paveway IV munitions to hit a several access tunnels leading to the depot... preliminary assessments suggest the target was engaged successfully," officials stated.
There was no sign of any civilian impact in the attack conducted Saturday night and every plane involved returned to base without incident, the defence officials confirmed.
The Typhoon FGR4s were supported by a Voyager tanker plane.
Daesh - alternatively referred to as the so-called Islamic State - established militant control over parts of Syria and Iraq prior to its 2019 collapse.
"This operation underscores our UK leadership, and commitment to stand shoulder to shoulder with our allies, to eliminate any re-emergence of the terrorist group and their dangerous and violent ideologies in the region," the British Defence Secretary John Healey said.
British military aircraft have conducted surveillance missions over Syrian airspace to "forestall any attempted comeback" of Islamic State subsequent to its routing at the climactic battle in Baghuz in the year 2019, the ministry said.
"I must thank every member of the UK armed forces who took part in this operation for their professionalism and their valour," he said. "Including them were numerous UK service members deployed over the holidays. This mission, to take out terrorist threats who threaten our way of life, shows how British military are prepared to act, throughout the year, protecting the UK within its borders and strong abroad."
Last December, the United States armed forces carried out what it termed a "major assault" on IS targets in the country, after an ambush killed two American soldiers and a civilian linguist in the Palmyra area.
The UN estimates Daesh still has between 5,000 and 7,000 fighters in Syria and Iraq.